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Increasingly, researchers are focusing on the role of poly-ubiquitin chains linked through K11. This post-translational modification has been linked to ERAD as a signal for proteasomal degradation. K11-linked chains appear to play an important role in cell cycle signaling, as they are associated with the anaphase promoting complex (APC). These tri-ubiquitin chains are generated from the enzymatic linkage of wild-type ubiquitin through lysine 11 and purified to >95% homogenity by ion exchange chromatography.
Species | Human |
Source | E. coli |
Tag | None |
Molecular Weight | 25,656 Da |
Quantity | 100 µg |
Concentration | Variable |
Formulation | 20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA |
Storage | -80°C, avoid freeze/thaw cycles |
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