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UBE2D1 is a 147 amino acid (16.6 kD) protein that mediates the degradation of abnormal proteins or proteins with short half-lives. It is a component of a Ubiquitin ligase complex including UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC, and TBL1X. It also functions in E6AP-mediated ubiquitylation of p53/TP53. UBE2D1 has been shown to interact with BARD1, UBE3A, and BRCA1.
Species | Human |
Source | E. coli |
Tag | His6-SUMO |
Molecular Weight | 28,621 Da (with tag) |
Quantity | 0.8 nmol, 3.0 nmol |
Concentration | 40 µM |
Formulation | 50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol |
Storage | -80°C, avoid freeze/thaw cycles |
LifeSensors成立于1996年,位于美国宾夕法尼亚州费城,是一家为药物发现与研究提供方法和可行性技术方法的生物技术公司。公司致力于为泛素和泛素蛋白酶体通路研究领域提供高品质的抗体、酶、蛋白质等试剂和试剂盒,产品最全、最新,是泛素研究者的最佳选择。其原核和真核蛋白表达系统SUMOpro和SUMOstar已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。通过提供创新的研究工具,LifeSensors已成为泛素和泛素样蛋白途径的领导者。